Cargando…

Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation

BACKGROUND: Celiac disease (CD) is caused by an uncontrolled immune response to gluten, a heterogeneous mixture of wheat storage proteins. The CD-toxicity of these proteins and their derived peptides is depending on the presence of specific T-cell epitopes (9-mer peptides; CD epitopes) that mediate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salentijn, Elma MJ, Mitea, D Cristina, Goryunova, Svetlana V, van der Meer, Ingrid M, Padioleau, Ismael, Gilissen, Luud JWJ, Koning, Frits, Smulders, Marinus JM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469346/ https://www.ncbi.nlm.nih.gov/pubmed/22726570 http://dx.doi.org/10.1186/1471-2164-13-277

Ejemplares similares

Quantitative and qualitative differences in celiac disease epitopes among durum wheat varieties identified through deep RNA-amplicon sequencing
por: Salentijn, Elma MJ, et al.
Publicado: (2013)

Expansion of the gamma-gliadin gene family in Aegilops and Triticum
por: Goryunova, Svetlana V, et al.
Publicado: (2012)

Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes
por: van Herpen, Teun WJM, et al.
Publicado: (2006)

A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease
por: Mitea, Cristina, et al.
Publicado: (2010)

Correction: A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease
por: Mitea, Cristina, et al.
Publicado: (2012)

Tetraploid and hexaploid wheat varieties reveal large differences in expression of alpha-gliadins from homoeologous Gli-2 loci
por: Salentijn, Elma MJ, et al.
Publicado: (2009)

Exploring the alpha‐gliadin locus: the 33‐mer peptide with six overlapping coeliac disease epitopes in Triticum aestivum is derived from a subgroup of Aegilops tauschii
por: Schaart, Jan G., et al.
Publicado: (2021)

Why Oats Are Safe and Healthy for Celiac Disease Patients
por: Gilissen, Luud J. W. J., et al.
Publicado: (2016)

Removing celiac disease-related gluten proteins from bread wheat while retaining technological properties: a study with Chinese Spring deletion lines
por: van den Broeck, Hetty C, et al.
Publicado: (2009)

Presence of celiac disease epitopes in modern and old hexaploid wheat varieties: wheat breeding may have contributed to increased prevalence of celiac disease
por: van den Broeck, Hetty C., et al.
Publicado: (2010)

Characterization of PR-10 genes from eight Betula species and detection of Bet v 1 isoforms in birch pollen
por: Schenk, Martijn F, et al.
Publicado: (2009)

Celiac Immunogenic Potential of α-Gliadin Epitope Variants from Triticum and Aegilops Species
por: Ruiz-Carnicer, Ángela, et al.
Publicado: (2019)

Genome-wide analysis of complex wheat gliadins, the dominant carriers of celiac disease epitopes
por: Wang, Da-Wei, et al.
Publicado: (2017)

Different levels of humoral immunoreactivity to different wheat cultivars gliadin are present in patients with celiac disease and in patients with multiple myeloma
por: Konic-Ristic, Aleksandra, et al.
Publicado: (2009)

Seven different genes encode a diverse mixture of isoforms of Bet v 1, the major birch pollen allergen
por: Schenk, Martijn F, et al.
Publicado: (2006)

Structural Perspective of Gliadin Peptides Active in Celiac Disease
por: Falcigno, Lucia, et al.
Publicado: (2020)

Pro-Inflammatory Nutrient: Focus on Gliadin and Celiac Disease
por: Barone, Maria Vittoria, et al.
Publicado: (2022)

Humoral immunoreactivity to gliadin and to tissue transglutaminase is present in some patients with multiple myeloma
por: Juranic, Zorica, et al.
Publicado: (2008)

The Intestinal T Cell Response to α-Gliadin in Adult Celiac Disease Is Focused on a Single Deamidated Glutamine Targeted by Tissue Transglutaminase
por: Arentz-Hansen, Helene, et al.
Publicado: (2000)

The gliadin-CFTR connection: new perspectives for the treatment of celiac disease
por: Maiuri, Luigi, et al.
Publicado: (2019)

Intestinal Epithelium Modulates Macrophage Response to Gliadin in Celiac Disease
por: Serena, Gloria, et al.
Publicado: (2019)

Celiac disease: quantity matters
por: Koning, Frits
Publicado: (2012)

Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules
por: Sollid, Ludvig M., et al.
Publicado: (2012)

The Tip of the “Celiac Iceberg” in China: A Systematic Review and Meta-Analysis
por: Yuan, Juanli, et al.
Publicado: (2013)

Application of Deamidated Gliadin Antibodies in the Follow-Up of Treated Celiac Disease
por: de Chaisemartin, Luc, et al.
Publicado: (2015)

Genistein antagonizes gliadin-induced CFTR malfunction in models of celiac disease
por: Esposito, Speranza, et al.
Publicado: (2019)

Monitoring of gluten-free diet compliance in celiac patients by assessment of gliadin 33-mer equivalent epitopes in feces(1)(2)(3)
por: Comino, Isabel, et al.
Publicado: (2012)

The Shutdown of Celiac Disease-Related Gliadin Epitopes in Bread Wheat by RNAi Provides Flours with Increased Stability and Better Tolerance to Over-Mixing
por: Gil-Humanes, Javier, et al.
Publicado: (2014)

Multiple Wheat Genomes Reveal Novel Gli-2 Sublocus Location and Variation of Celiac Disease Epitopes in Duplicated α-Gliadin Genes
por: Halstead-Nussloch, Gwyneth, et al.
Publicado: (2021)

Changes in Non-Deamidated versus Deamidated Epitope Targeting and Disease Prediction during the Antibody Response to Gliadin and Transglutaminase of Infants at Risk for Celiac Disease
por: Diós, Ádám, et al.
Publicado: (2022)

Exploring T Cell Reactivity to Gliadin in Young Children with Newly Diagnosed Celiac Disease
por: Liu, Edwin, et al.
Publicado: (2014)

The α-Gliadins in Bread Wheat: Effect of Nitrogen Treatment on the Expression of the Major Celiac Disease Immunogenic Complex in Two RNAi Low-Gliadin Lines
por: Sánchez-León, Susana, et al.
Publicado: (2021)

Effect of Gliadin on Permeability of Intestinal Biopsy Explants from Celiac Disease Patients and Patients with Non-Celiac Gluten Sensitivity
por: Hollon, Justin, et al.
Publicado: (2015)

Trehalose Modulates Autophagy Process to Counteract Gliadin Cytotoxicity in an In Vitro Celiac Disease Model
por: Manai, Federico, et al.
Publicado: (2019)

Gliadin Sequestration as a Novel Therapy for Celiac Disease: A Prospective Application for Polyphenols
por: Van Buiten, Charlene B., et al.
Publicado: (2021)

Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity
por: Scherf, Katharina A., et al.
Publicado: (2020)

Gliadin-Mediated Proliferation and Innate Immune Activation in Celiac Disease Are Due to Alterations in Vesicular Trafficking
por: Barone, M. Vittoria, et al.
Publicado: (2011)

Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity
por: Caio, Giacomo, et al.
Publicado: (2014)

Gliadin Peptides as Triggers of the Proliferative and Stress/Innate Immune Response of the Celiac Small Intestinal Mucosa
por: Barone, Maria Vittoria, et al.
Publicado: (2014)

Constitutive alterations in vesicular trafficking increase the sensitivity of cells from celiac disease patients to gliadin
por: Lania, Giuliana, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_r9qmdgpogjs388sgc3nslagmv2