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Use of Pleiotropy to Model Genetic Interactions in a Population

Systems-level genetic studies in humans and model systems increasingly involve both high-resolution genotyping and multi-dimensional quantitative phenotyping. We present a novel method to infer and interpret genetic interactions that exploits the complementary information in multiple phenotypes. We...

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Detalles Bibliográficos
Autores principales: Carter, Gregory W., Hays, Michelle, Sherman, Amir, Galitski, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469415/
https://www.ncbi.nlm.nih.gov/pubmed/23071457
http://dx.doi.org/10.1371/journal.pgen.1003010