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Use of Pleiotropy to Model Genetic Interactions in a Population
Systems-level genetic studies in humans and model systems increasingly involve both high-resolution genotyping and multi-dimensional quantitative phenotyping. We present a novel method to infer and interpret genetic interactions that exploits the complementary information in multiple phenotypes. We...
Autores principales: | Carter, Gregory W., Hays, Michelle, Sherman, Amir, Galitski, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469415/ https://www.ncbi.nlm.nih.gov/pubmed/23071457 http://dx.doi.org/10.1371/journal.pgen.1003010 |
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