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Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation
An outstanding question in human genetics has been the degree to which adaptation occurs from standing genetic variation or from de novo mutations. Here, we combine several common statistics used to detect selection in an Approximate Bayesian Computation (ABC) framework, with the goal of discriminat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469416/ https://www.ncbi.nlm.nih.gov/pubmed/23071458 http://dx.doi.org/10.1371/journal.pgen.1003011 |