MOSAIC: A Multiscale Model of Osteogenesis and Sprouting Angiogenesis with Lateral Inhibition of Endothelial Cells

The healing of a fracture depends largely on the development of a new blood vessel network (angiogenesis) in the callus. During angiogenesis tip cells lead the developing sprout in response to extracellular signals, amongst which vascular endothelial growth factor (VEGF) is critical. In order to ens...

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Detalles Bibliográficos
Autores principales: Carlier, Aurélie, Geris, Liesbet, Bentley, Katie, Carmeliet, Geert, Carmeliet, Peter, Van Oosterwyck, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469420/
https://www.ncbi.nlm.nih.gov/pubmed/23071433
http://dx.doi.org/10.1371/journal.pcbi.1002724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469420/
https://www.ncbi.nlm.nih.gov/pubmed/23071433
http://dx.doi.org/10.1371/journal.pcbi.1002724

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