Connecting Macroscopic Observables and Microscopic Assembly Events in Amyloid Formation Using Coarse Grained Simulations

The pre-fibrillar stages of amyloid formation have been implicated in cellular toxicity, but have proved to be challenging to study directly in experiments and simulations. Rational strategies to suppress the formation of toxic amyloid oligomers require a better understanding of the mechanisms by wh...

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Detalles Bibliográficos
Autores principales: Bieler, Noah S., Knowles, Tuomas P. J., Frenkel, Daan, Vácha, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469425/
https://www.ncbi.nlm.nih.gov/pubmed/23071427
http://dx.doi.org/10.1371/journal.pcbi.1002692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469425/
https://www.ncbi.nlm.nih.gov/pubmed/23071427
http://dx.doi.org/10.1371/journal.pcbi.1002692

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