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Harnessing the power of transposon mutagenesis for antibacterial target identification and evaluation
Determining the mechanism of action of bacterial growth inhibitors can be a formidable challenge in the progression of small molecules into antibacterial therapies. To help address this bottleneck, we have developed a robust transposon mutagenesis system using a suite of outward facing promoters in...
Autores principales: | Meredith, Timothy C., Wang, Hao, Beaulieu, Patrick, Gründling, Angelika, Roemer, Terry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469428/ https://www.ncbi.nlm.nih.gov/pubmed/23094235 http://dx.doi.org/10.4161/mge.21647 |
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