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Increasing Signal Specificity of the TOL Network of Pseudomonas putida mt-2 by Rewiring the Connectivity of the Master Regulator XylR

Prokaryotic transcription factors (TFs) that bind small xenobiotic molecules (e.g., TFs that drive genes that respond to environmental pollutants) often display a promiscuous effector profile for analogs of the bona fide chemical signals. XylR, the master TF for expression of the m-xylene biodegrada...

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Detalles Bibliográficos
Autores principales: de las Heras, Aitor, Fraile, Sofia, de Lorenzo, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469447/
https://www.ncbi.nlm.nih.gov/pubmed/23071444
http://dx.doi.org/10.1371/journal.pgen.1002963