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Comparison of Family History and SNPs for Predicting Risk of Complex Disease

The clinical utility of family history and genetic tests is generally well understood for simple Mendelian disorders and rare subforms of complex diseases that are directly attributable to highly penetrant genetic variants. However, little is presently known regarding the performance of these method...

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Detalles Bibliográficos
Autores principales: Do, Chuong B., Hinds, David A., Francke, Uta, Eriksson, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469463/
https://www.ncbi.nlm.nih.gov/pubmed/23071447
http://dx.doi.org/10.1371/journal.pgen.1002973