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Staphylococcus aureus Proteins Sbi and Efb Recruit Human Plasmin to Degrade Complement C3 and C3b

Upon host infection, the human pathogenic microbe Staphylococcus aureus (S. aureus) immediately faces innate immune reactions such as the activated complement system. Here, a novel innate immune evasion strategy of S. aureus is described. The staphylococcal proteins surface immunoglobulin-binding pr...

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Detalles Bibliográficos
Autores principales: Koch, Tina K., Reuter, Michael, Barthel, Diana, Böhm, Sascha, van den Elsen, Jean, Kraiczy, Peter, Zipfel, Peter F., Skerka, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469469/
https://www.ncbi.nlm.nih.gov/pubmed/23071827
http://dx.doi.org/10.1371/journal.pone.0047638