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CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer

Aberrant promoter region hypermethylation of upstream transcription factors may be responsible for silencing entire anti-neoplastic gene networks. In this study, we explored whether transcription factor coding gene, caudal-related homeobox 2 (CDX2), is silenced by promoter hypermethylation in lung c...

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Detalles Bibliográficos
Autores principales: Liu, Xuefeng, Zhang, Xiaomei, Zhan, Qimin, Brock, Malcolm V., Herman, James G., Guo, Mingzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469472/
https://www.ncbi.nlm.nih.gov/pubmed/22892849
http://dx.doi.org/10.4161/cbt.21344