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CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer
Aberrant promoter region hypermethylation of upstream transcription factors may be responsible for silencing entire anti-neoplastic gene networks. In this study, we explored whether transcription factor coding gene, caudal-related homeobox 2 (CDX2), is silenced by promoter hypermethylation in lung c...
Autores principales: | Liu, Xuefeng, Zhang, Xiaomei, Zhan, Qimin, Brock, Malcolm V., Herman, James G., Guo, Mingzhou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469472/ https://www.ncbi.nlm.nih.gov/pubmed/22892849 http://dx.doi.org/10.4161/cbt.21344 |
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