Cargando…

Severe Thymic Atrophy in a Mouse Model of Skin Inflammation Accounts for Impaired TNFR1 Signaling

Transgenic mice expressing the caspase-cleaved form of the tyrosine kinase Lyn (LynΔN) develop a TNFα-dependent skin disease that accurately recapitulates human psoriasis. Participation of lymphocytes in this disease was confirmed by backcrossing LynΔN mice on a Rag-1 deficient background. The prese...

Descripción completa

Detalles Bibliográficos
Autores principales:	Belhacéne, Nathalie, Gamas, Parvati, Gonçalvès, Diogo, Jacquin, Marie, Beneteau, Marie, Jacquel, Arnaud, Colosetti, Pascal, Ricci, Jean-Ehrland, Wakkach, Abdellilah, Auberger, Patrick, Marchetti, Sandrine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469485/ https://www.ncbi.nlm.nih.gov/pubmed/23071785 http://dx.doi.org/10.1371/journal.pone.0047321

Ejemplares similares

The small heat shock protein B8 (HSPB8) confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells
por: Hamouda, Mohamed-Amine, et al.
Publicado: (2014)

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells
por: Dufies, Maeva, et al.
Publicado: (2011)

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death
por: Dubois, Alix, et al.
Publicado: (2016)

Acadesine Kills Chronic Myelogenous Leukemia (CML) Cells through PKC-Dependent Induction of Autophagic Cell Death
por: Robert, Guillaume, et al.
Publicado: (2009)

A new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function
por: Puissant, A, et al.
Publicado: (2014)

Chaperone-Mediated Autophagy and Its Emerging Role in Hematological Malignancies
por: Robert, Guillaume, et al.
Publicado: (2019)

Implication and Regulation of AMPK during Physiological and Pathological Myeloid Differentiation
por: Jacquel, Arnaud, et al.
Publicado: (2018)

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice
por: Hamouda, Mohamed-Amine, et al.
Publicado: (2016)

Infection-Associated Thymic Atrophy
por: Luo, Mingli, et al.
Publicado: (2021)

Rac1 Deletion Causes Thymic Atrophy
por: Hunziker, Lukas, et al.
Publicado: (2011)

Correction: Rac1 Deletion Causes Thymic Atrophy
por: Hunziker, Lukas, et al.
Publicado: (2011)

Activation of TNFR2 sensitizes macrophages for TNFR1-mediated necroptosis
por: Siegmund, Daniela, et al.
Publicado: (2016)

TNFR1 and TNFR2 in the Control of the Life and Death Balance of Macrophages
por: Wajant, Harald, et al.
Publicado: (2019)

Fn14 and TNFR2 as regulators of cytotoxic TNFR1 signaling
por: Siegmund, Daniela, et al.
Publicado: (2023)

Escherichia coli α-Hemolysin Counteracts the Anti-Virulence Innate Immune Response Triggered by the Rho GTPase Activating Toxin CNF1 during Bacteremia
por: Diabate, Mamady, et al.
Publicado: (2015)

The generation, activation, and polarization of monocyte-derived macrophages in human malignancies
por: Chaintreuil, Paul, et al.
Publicado: (2023)

Transmembrane TNF and Its Receptors TNFR1 and TNFR2 in Mycobacterial Infections
por: Ruiz, Andy, et al.
Publicado: (2021)

Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis
por: Fiedler, Timon, et al.
Publicado: (2023)

Gut region-specific TNFR expression: TNFR2 is more affected than TNFR1 in duodenal myenteric ganglia of diabetic rats
por: Barta, Bence Pál, et al.
Publicado: (2023)

Gender-Related Differences in the Rates of Age Associated Thymic Atrophy
por: Aspinall, Richard, et al.
Publicado: (2001)

Gonadal atrophy as a cause of thymic hyperplasia after chemotherapy.
por: Sperandio, P., et al.
Publicado: (1996)

Prevention of thymic atrophy in mammary tumor bearers by IFN-gamma
por: Charyulu, V, et al.
Publicado: (2001)

IL-34 and CSF-1 display an equivalent macrophage differentiation ability but a different polarization potential
por: Boulakirba, Sonia, et al.
Publicado: (2018)

Precambrian origins of the TNFR superfamily
por: Quistad, S D, et al.
Publicado: (2016)

TNFR1 and TNFR2 regulate the extrinsic apoptotic pathway in myeloma cells by multiple mechanisms
por: Rauert, H, et al.
Publicado: (2011)

Sphingosine-1 phosphate promotes thymic atrophy during sepsis progression
por: Kuchler, L, et al.
Publicado: (2014)

Interleukin-21 Accelerates Thymic Recovery from Glucocorticoïd-Induced Atrophy
por: Rafei, Moutih, et al.
Publicado: (2013)

Epigenetic modifications in thymic epithelial cells: an evolutionary perspective for thymus atrophy
por: Hu, Cexun, et al.
Publicado: (2021)

Dynamics of T cell receptor distributions following acute thymic atrophy and resumption
por: Lewkiewicz, Stephanie M., et al.
Publicado: (2019)

ATP-competitive Plk1 inhibitors induce caspase 3-mediated Plk1 cleavage and activation in hematopoietic cell lines
por: Dufies, Maeva, et al.
Publicado: (2017)

Differential Expression, Shedding, Cytokine Regulation and Function of TNFR1 and TNFR2 in Human Fetal Astrocytes
por: Choi, Sun Ju, et al.
Publicado: (2005)

Preclinical and clinical aspects of TNF-α and its receptors TNFR1 and TNFR2 in breast cancer
por: Martínez-Reza, Isela, et al.
Publicado: (2017)

Alleviation of Ultraviolet-B Radiation-Induced Photoaging by a TNFR Antagonistic Peptide, TNFR2-SKE
por: Lee, Kyoung-Jin, et al.
Publicado: (2019)

Leukocyte TNFR1 and TNFR2 Expression Contributes to the Peripheral Immune Response in Cases with Ischemic Stroke
por: Hansen, Rikke B., et al.
Publicado: (2021)

Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice
por: Liang, Yuejin, et al.
Publicado: (2022)

The Roles of TNFR2 Signaling in Cancer Cells and the Tumor Microenvironment and the Potency of TNFR2 Targeted Therapy
por: Takahashi, Hiroyuki, et al.
Publicado: (2022)

Reprogramming monocyte-derived macrophages through caspase inhibition
por: Chaintreuil, Paul, et al.
Publicado: (2021)

Autoimmune-Mediated Thymic Atrophy Is Accelerated but Reversible in RelB-Deficient Mice
por: O’Sullivan, Brendan J., et al.
Publicado: (2018)

TNFR2: The new Treg switch?
por: Cohen, José L., et al.
Publicado: (2017)

Editorial: TNFR Superfamily Oligomerization and Signaling
por: Micheau, Olivier, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tq1u4915brd4btpe84m68aue3g