Pms2 Suppresses Large Expansions of the (GAA·TTC)(n) Sequence in Neuronal Tissues

Expanded trinucleotide repeat sequences are the cause of several inherited neurodegenerative diseases. Disease pathogenesis is correlated with several features of somatic instability of these sequences, including further large expansions in postmitotic tissues. The presence of somatic expansions in...

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Detalles Bibliográficos
Autores principales: Bourn, Rebecka L., De Biase, Irene, Pinto, Ricardo Mouro, Sandi, Chiranjeevi, Al-Mahdawi, Sahar, Pook, Mark A., Bidichandani, Sanjay I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469490/
https://www.ncbi.nlm.nih.gov/pubmed/23071719
http://dx.doi.org/10.1371/journal.pone.0047085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469490/
https://www.ncbi.nlm.nih.gov/pubmed/23071719
http://dx.doi.org/10.1371/journal.pone.0047085

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