DNA Polymerase α (swi7) and the Flap Endonuclease Fen1 (rad2) Act Together in the S-Phase Alkylation Damage Response in S. pombe

Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching. Here we investigate whether this mutation conf...

Descripción completa

Detalles Bibliográficos
Autores principales: Koulintchenko, Milana, Vengrova, Sonya, Eydmann, Trevor, Arumugam, Prakash, Dalgaard, Jacob Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469492/
https://www.ncbi.nlm.nih.gov/pubmed/23071723
http://dx.doi.org/10.1371/journal.pone.0047091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469492/
https://www.ncbi.nlm.nih.gov/pubmed/23071723
http://dx.doi.org/10.1371/journal.pone.0047091

Ejemplares similares