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DNA Polymerase α (swi7) and the Flap Endonuclease Fen1 (rad2) Act Together in the S-Phase Alkylation Damage Response in S. pombe

Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching. Here we investigate whether this mutation conf...

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Detalles Bibliográficos
Autores principales:	Koulintchenko, Milana, Vengrova, Sonya, Eydmann, Trevor, Arumugam, Prakash, Dalgaard, Jacob Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469492/ https://www.ncbi.nlm.nih.gov/pubmed/23071723 http://dx.doi.org/10.1371/journal.pone.0047091

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