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Ergosterol content specifies targeting of tail-anchored proteins to mitochondrial outer membranes

Tail-anchored (TA) proteins have a single C-terminal transmembrane domain, making their biogenesis dependent on posttranslational translocation. Despite their importance, no dedicated insertion machinery has been uncovered for mitochondrial outer membrane (MOM) TA proteins. To decipher the molecular...

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Detalles Bibliográficos
Autores principales: Krumpe, Katrin, Frumkin, Idan, Herzig, Yonatan, Rimon, Nitzan, Özbalci, Cagakan, Brügger, Britta, Rapaport, Doron, Schuldiner, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469509/
https://www.ncbi.nlm.nih.gov/pubmed/22918956
http://dx.doi.org/10.1091/mbc.E11-12-0994