APC(FZR1) prevents nondisjunction in mouse oocytes by controlling meiotic spindle assembly timing

FZR1 is an anaphase-promoting complex (APC) activator best known for its role in the mitotic cell cycle at M-phase exit, in G1, and in maintaining genome integrity. Previous studies also established that it prevents meiotic resumption, equivalent to the G2/M transition. Here we report that mouse ooc...

Descripción completa

Detalles Bibliográficos
Autores principales: Holt, Janet E., Lane, Simon I. R., Jennings, Phoebe, García-Higuera, Irene, Moreno, Sergio, Jones, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469513/
https://www.ncbi.nlm.nih.gov/pubmed/22918942
http://dx.doi.org/10.1091/mbc.E12-05-0352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469513/
https://www.ncbi.nlm.nih.gov/pubmed/22918942
http://dx.doi.org/10.1091/mbc.E12-05-0352

Ejemplares similares