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Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism
Rho GTPases share a common inhibitor, Rho guanine nucleotide dissociation inhibitor (RhoGDI), which regulates their expression levels, membrane localization, and activation state. The selective dissociation of individual Rho GTPases from RhoGDI ensures appropriate responses to cellular signals, but...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469516/ https://www.ncbi.nlm.nih.gov/pubmed/22918940 http://dx.doi.org/10.1091/mbc.E12-01-0026 |