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Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism

Rho GTPases share a common inhibitor, Rho guanine nucleotide dissociation inhibitor (RhoGDI), which regulates their expression levels, membrane localization, and activation state. The selective dissociation of individual Rho GTPases from RhoGDI ensures appropriate responses to cellular signals, but...

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Detalles Bibliográficos
Autores principales: Ard, Ryan, Mulatz, Kirk, Abramovici, Hanan, Maillet, Jean-Christian, Fottinger, Alexandra, Foley, Tanya, Byham, Michèle-Renée, Iqbal, Tasfia Ahmed, Yoneda, Atsuko, Couchman, John R., Parks, Robin J., Gee, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469516/
https://www.ncbi.nlm.nih.gov/pubmed/22918940
http://dx.doi.org/10.1091/mbc.E12-01-0026