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RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4

The GTPase RhoA is a central regulator of cellular contractility in a wide variety of biological processes. During these events, RhoA is activated by guanine nucleotide exchange factors (GEFs). These molecules are highly regulated to ensure that RhoA activation occurs at the proper time and place. D...

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Detalles Bibliográficos
Autores principales: Tse, Yu Chung, Werner, Michael, Longhini, Katrina M., Labbe, Jean-Claude, Goldstein, Bob, Glotzer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469517/
https://www.ncbi.nlm.nih.gov/pubmed/22918944
http://dx.doi.org/10.1091/mbc.E12-04-0268