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Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of...

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Detalles Bibliográficos
Autores principales: de Vries, Margreet R., Niessen, Hans W. M., Löwik, Clemens W. G. M., Hamming, Jaap F., Jukema, J. Wouter, Quax, Paul H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469549/
https://www.ncbi.nlm.nih.gov/pubmed/23071737
http://dx.doi.org/10.1371/journal.pone.0047134