Double Domain Swapping in Bovine Seminal RNase: Formation of Distinct N- and C-swapped Tetramers and Multimers with Increasing Biological Activities

Bovine seminal (BS) RNase, the unique natively dimeric member of the RNase super-family, represents a special case not only for its additional biological actions but also for the singular features of 3D domain swapping. The native enzyme is indeed a mixture of two isoforms: M = M, a dimer held toget...

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Detalles Bibliográficos
Autores principales: Gotte, Giovanni, Mahmoud Helmy, Alexander, Ercole, Carmine, Spadaccini, Roberta, Laurents, Douglas V., Donadelli, Massimo, Picone, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469567/
https://www.ncbi.nlm.nih.gov/pubmed/23071641
http://dx.doi.org/10.1371/journal.pone.0046804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469567/
https://www.ncbi.nlm.nih.gov/pubmed/23071641
http://dx.doi.org/10.1371/journal.pone.0046804

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