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Similarities between Exogenously- and Endogenously-Induced Envelope Stress: The Effects of a New Antibacterial Molecule, TPI1609-10

Antibiotics with novel and/or multiple targets are highly desirable in the face of the steady rise of clinical antibiotic resistance. We have screened and identified small molecules, typified by the compound TPI1609-10 (aka SM10), with antibiotic activity against both gram-positive and gram-negative...

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Detalles Bibliográficos
Autores principales: Yitzhaki, Shmuel, Rostron, Jason E., Xu, Yan, Rideout, Marc C., Authement, R. Nathan, Barlow, Steven B., Segall, Anca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469575/
https://www.ncbi.nlm.nih.gov/pubmed/23071502
http://dx.doi.org/10.1371/journal.pone.0044896