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Investigation of FGFR2-IIIC Signaling via FGF-2 Ligand for Advancing GCT Stromal Cell Differentiation

Giant cell tumor of bone (GCT) is an aggressive bone tumor consisting of multinucleated osteoclast-like giant cells and proliferating osteoblast-like stromal cells. The signaling mechanism involved in GCT stromal cell osteoblastic differentiation is not fully understood. Previous work in our lab rep...

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Detalles Bibliográficos
Autores principales: Singh, Shalini, Singh, Mohini, Mak, Isabella W. Y., Turcotte, Robert, Ghert, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469652/
https://www.ncbi.nlm.nih.gov/pubmed/23071632
http://dx.doi.org/10.1371/journal.pone.0046769