The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b

CDK9, the kinase of positive transcription elongation factor b (P-TEFb), stimulates transcription elongation by phosphorylating RNA polymerase II and transcription elongation factors. Using kinetic analysis of a human P-TEFb complex consisting of CDK9 and cyclin T, we show that the CDK9 C-terminal t...

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Detalles Bibliográficos
Autores principales: Baumli, Sonja, Hole, Alison J., Wang, Lan-Zhen, Noble, Martin E.M., Endicott, Jane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469819/
https://www.ncbi.nlm.nih.gov/pubmed/22959624
http://dx.doi.org/10.1016/j.str.2012.08.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469819/
https://www.ncbi.nlm.nih.gov/pubmed/22959624
http://dx.doi.org/10.1016/j.str.2012.08.011

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