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The CDK9 Tail Determines the Reaction Pathway of Positive Transcription Elongation Factor b
CDK9, the kinase of positive transcription elongation factor b (P-TEFb), stimulates transcription elongation by phosphorylating RNA polymerase II and transcription elongation factors. Using kinetic analysis of a human P-TEFb complex consisting of CDK9 and cyclin T, we show that the CDK9 C-terminal t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469819/ https://www.ncbi.nlm.nih.gov/pubmed/22959624 http://dx.doi.org/10.1016/j.str.2012.08.011 |