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ATP-Driven Remodeling of the Linker Domain in the Dynein Motor

Dynein ATPases are the largest known cytoskeletal motors and perform critical functions in cells: carrying cargo along microtubules in the cytoplasm and powering flagellar beating. Dyneins are members of the AAA+ superfamily of ring-shaped enzymes, but how they harness this architecture to produce m...

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Detalles Bibliográficos
Autores principales: Roberts, Anthony J., Malkova, Bara, Walker, Matt L., Sakakibara, Hitoshi, Numata, Naoki, Kon, Takahide, Ohkura, Reiko, Edwards, Thomas A., Knight, Peter J., Sutoh, Kazuo, Oiwa, Kazuhiro, Burgess, Stan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469822/
https://www.ncbi.nlm.nih.gov/pubmed/22863569
http://dx.doi.org/10.1016/j.str.2012.07.003