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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding

The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin in rats leads to significant binding of muscarinic rec...

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Detalles Bibliográficos
Autores principales: Yamada, Shizuo, Kuraoka, Shiori, Osano, Ayaka, Ito, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469828/
https://www.ncbi.nlm.nih.gov/pubmed/23094215
http://dx.doi.org/10.5213/inj.2012.16.3.107