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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin in rats leads to significant binding of muscarinic rec...
Autores principales: | Yamada, Shizuo, Kuraoka, Shiori, Osano, Ayaka, Ito, Yoshihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Continence Society
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469828/ https://www.ncbi.nlm.nih.gov/pubmed/23094215 http://dx.doi.org/10.5213/inj.2012.16.3.107 |
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