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SNP-SNP Interactions Discovered by Logic Regression Explain Crohn's Disease Genetics

In genome-wide association studies (GWAS), the association between each single nucleotide polymorphism (SNP) and a phenotype is assessed statistically. To further explore genetic associations in GWAS, we considered two specific forms of biologically plausible SNP-SNP interactions, ‘SNP intersection’...

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Detalles Bibliográficos
Autores principales: Dinu, Irina, Mahasirimongkol, Surakameth, Liu, Qi, Yanai, Hideki, Sharaf Eldin, Noha, Kreiter, Erin, Wu, Xuan, Jabbari, Shahab, Tokunaga, Katsushi, Yasui, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470545/
https://www.ncbi.nlm.nih.gov/pubmed/23071489
http://dx.doi.org/10.1371/journal.pone.0043035