Mining Pure, Strict Epistatic Interactions from High-Dimensional Datasets: Ameliorating the Curse of Dimensionality

BACKGROUND: The interaction between loci to affect phenotype is called epistasis. It is strict epistasis if no proper subset of the interacting loci exhibits a marginal effect. For many diseases, it is likely that unknown epistatic interactions affect disease susceptibility. A difficulty when mining...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Neapolitan, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470561/
https://www.ncbi.nlm.nih.gov/pubmed/23071633
http://dx.doi.org/10.1371/journal.pone.0046771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470561/
https://www.ncbi.nlm.nih.gov/pubmed/23071633
http://dx.doi.org/10.1371/journal.pone.0046771

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