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Computational Modeling Reveals Dendritic Origins of GABA(A)-Mediated Excitation in CA1 Pyramidal Neurons

GABA is the key inhibitory neurotransmitter in the adult central nervous system, but in some circumstances can lead to a paradoxical excitation that has been causally implicated in diverse pathologies from endocrine stress responses to diseases of excitability including neuropathic pain and temporal...

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Detalles Bibliográficos
Autores principales: Lewin, Naomi, Aksay, Emre, Clancy, Colleen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470566/
https://www.ncbi.nlm.nih.gov/pubmed/23071770
http://dx.doi.org/10.1371/journal.pone.0047250