Targeting the Oncogenic E3 Ligase Skp2 in Prostate and Breast Cancer Cells with a Novel Energy Restriction-Mimetic Agent

Substantial evidence supports the oncogenic role of the E3 ubiquitin ligase S-phase kinase-associated protein 2 (Skp2) in many types of cancers through its ability to target a broad range of signaling effectors for ubiquitination. Thus, this oncogenic E3 ligase represents an important target for can...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Shuo, Chu, Po-Chen, Chuang, Hsiao-Ching, Hung, Wen-Chun, Kulp, Samuel K., Chen, Ching-Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470570/
https://www.ncbi.nlm.nih.gov/pubmed/23071779
http://dx.doi.org/10.1371/journal.pone.0047298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470570/
https://www.ncbi.nlm.nih.gov/pubmed/23071779
http://dx.doi.org/10.1371/journal.pone.0047298

Ejemplares similares