TRPM2 Cation Channels Modulate T Cell Effector Functions and Contribute to Autoimmune CNS Inflammation

TRPM2, a highly Ca(2+)-permeable member of the transient receptor potential melastatin-related (TRPM) family of cation channels, is expressed in cells of the immune system. We demonstrate firstly that TRPM2 cation channels on T cells critically influence T cell proliferation and proinflammatory cyto...

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Detalles Bibliográficos
Autores principales: Melzer, Nico, Hicking, Gordon, Göbel, Kerstin, Wiendl, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470594/
https://www.ncbi.nlm.nih.gov/pubmed/23077651
http://dx.doi.org/10.1371/journal.pone.0047617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470594/
https://www.ncbi.nlm.nih.gov/pubmed/23077651
http://dx.doi.org/10.1371/journal.pone.0047617

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