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Predicting the Outcome of Infectious Diseases: Variability among Inbred Mice as a New and Powerful Tool for Biomarker Discovery

Individuals respond differently to infectious diseases. Even among inbred mice that are presumed to be genetically identical, the response to a microbial pathogen is variable, which is generally thought to reflect experimental inconsistencies, technical errors, and stochastic processes. Here we desc...

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Detalles Bibliográficos
Autores principales: Martin, Miriam E., Dieter, Jacquelyn A., Luo, Zheng, Baumgarth, Nicole, Solnick, Jay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470649/
https://www.ncbi.nlm.nih.gov/pubmed/23073762
http://dx.doi.org/10.1128/mBio.00199-12