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The metastatic niche and stromal progression
The tumor stroma is comprised of extracellular matrix, non-malignant cells, and the signaling molecules they produce. It is an integral and vital component of primary tumors that together with the underlying genetic defects in the tumor cells determines the growth characteristics, morphology, and in...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer US
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470821/ https://www.ncbi.nlm.nih.gov/pubmed/22699312 http://dx.doi.org/10.1007/s10555-012-9373-9 |