Identification of BACE2 as an avid ß-amyloid-degrading protease

BACKGROUND: Proteases that degrade the amyloid ß-protein (Aß) have emerged as key players in the etiology and potential treatment of Alzheimer’s disease (AD), but it is unlikely that all such proteases have been identified. To discover new Aß-degrading proteases (AßDPs), we conducted an unbiased, ge...

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Detalles Bibliográficos
Autores principales: Abdul-Hay, Samer O, Sahara, Tomoko, McBride, Melinda, Kang, Dongcheul, Leissring, Malcolm A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470943/
https://www.ncbi.nlm.nih.gov/pubmed/22986058
http://dx.doi.org/10.1186/1750-1326-7-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470943/
https://www.ncbi.nlm.nih.gov/pubmed/22986058
http://dx.doi.org/10.1186/1750-1326-7-46

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