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Mycophenolate mofetil and FK506 have different effects on kidney allograft fibrosis in rats that underwent chronic allograft nephropathy

BACKGROUND: Tacrolimus (FK506) is associated with renal fibrosis in long-term use. Mycophenolatemofetil (MMF) can also inhibit or attenuate the progression of renal fibrosis. This study aimed to determine the different effects of FK506 and MMF on fibrosis-associated genes in the kidney in rats that...

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Detalles Bibliográficos
Autores principales: Luo, Lei, Sun, Zhaolin, Wu, Weidong, Luo, Guangheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470947/
https://www.ncbi.nlm.nih.gov/pubmed/22747784
http://dx.doi.org/10.1186/1471-2369-13-53