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Comprehensive predictions of target proteins based on protein-chemical interaction using virtual screening and experimental verifications
BACKGROUND: Identification of the target proteins of bioactive compounds is critical for elucidating the mode of action; however, target identification has been difficult in general, mostly due to the low sensitivity of detection using affinity chromatography followed by CBB staining and MS/MS analy...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471015/ https://www.ncbi.nlm.nih.gov/pubmed/22480302 http://dx.doi.org/10.1186/1472-6769-12-2 |