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Codon Preference Optimization Increases Prokaryotic Cystatin C Expression

Gene expression is closely related to optimal vector-host system pairing in many prokaryotes. Redesign of the human cystatin C (cysC) gene using the preferred codons of the prokaryotic system may significantly increase cysC expression in Escherichia coli (E. coli). Specifically, cysC expression may...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Mei, Cui, Zhen, Honghua, Zhu, Jess
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471025/
https://www.ncbi.nlm.nih.gov/pubmed/23093857
http://dx.doi.org/10.1155/2012/732017