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Controlling Self-Renewal and Differentiation of Stem Cells via Mechanical Cues
The control of stem cell response in vitro, including self-renewal and lineage commitment, has been proved to be directed by mechanical cues, even in the absence of biochemical stimuli. Through integrin-mediated focal adhesions, cells are able to anchor onto the underlying substrate, sense the surro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471035/ https://www.ncbi.nlm.nih.gov/pubmed/23091358 http://dx.doi.org/10.1155/2012/797410 |