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The effects of low-dose Nepsilon-(carboxymethyl)lysine (CML) and Nepsilon-(carboxyethyl)lysine (CEL), two main glycation free adducts considered as potential uremic toxins, on endothelial progenitor cell function

BACKGROUND: Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD). Endothelial progenitor cell (EPCs) dysfunction plays a key role in this pathogenesis. Uremic retention toxins have been reported to be in associated with EPC dysfunction. Advanced glycation end-p...

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Detalles Bibliográficos
Autores principales: Zhu, Jinzhou, Yang, Ke, Jing, Yajun, Du, Run, Zhu, Zhenbin, Lu, Lin, Zhang, Ruiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471041/
https://www.ncbi.nlm.nih.gov/pubmed/22853433
http://dx.doi.org/10.1186/1475-2840-11-90