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p120-catenin binding masks an endocytic signal conserved in classical cadherins

p120-catenin (p120) binds to the cytoplasmic tails of classical cadherins and inhibits cadherin endocytosis. Although p120 regulation of cadherin internalization is thought to be important for adhesive junction dynamics, the mechanism by which p120 modulates cadherin endocytosis is unknown. In this...

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Detalles Bibliográficos
Autores principales: Nanes, Benjamin A., Chiasson-MacKenzie, Christine, Lowery, Anthony M., Ishiyama, Noboru, Faundez, Victor, Ikura, Mitsuhiko, Vincent, Peter A., Kowalczyk, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471230/
https://www.ncbi.nlm.nih.gov/pubmed/23071156
http://dx.doi.org/10.1083/jcb.201205029