Cargando…

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...

Descripción completa

Detalles Bibliográficos
Autores principales: Manova, Vasilissa, Singh, Satyendra K, Iliakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471266/
https://www.ncbi.nlm.nih.gov/pubmed/22908892
http://dx.doi.org/10.1186/2041-9414-3-4