Cargando…
Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471266/ https://www.ncbi.nlm.nih.gov/pubmed/22908892 http://dx.doi.org/10.1186/2041-9414-3-4 |