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Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...

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Detalles Bibliográficos
Autores principales:	Manova, Vasilissa, Singh, Satyendra K, Iliakis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471266/ https://www.ncbi.nlm.nih.gov/pubmed/22908892 http://dx.doi.org/10.1186/2041-9414-3-4

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