Cargando…

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manova, Vasilissa, Singh, Satyendra K, Iliakis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471266/ https://www.ncbi.nlm.nih.gov/pubmed/22908892 http://dx.doi.org/10.1186/2041-9414-3-4

Ejemplares similares

ZEB1 promotes non-homologous end joining double-strand break repair
por: Genetta, Thomas L, et al.
Publicado: (2023)

One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
por: Ensminger, Michael, et al.
Publicado: (2020)

Inhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extracts
por: Diggle, C. P., et al.
Publicado: (2005)

A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks
por: Hatkevich, Talia, et al.
Publicado: (2021)

Post-irradiation chemical processing of DNA damage generates double-strand breaks in cells already engaged in repair
por: Singh, Satyendra K., et al.
Publicado: (2011)

The Efficiency of Homologous Recombination and Non-Homologous End Joining Systems in Repairing Double-Strand Breaks during Cell Cycle Progression
por: Bee, Leonardo, et al.
Publicado: (2013)

Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents
por: Zaboikin, Michail, et al.
Publicado: (2017)

Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joining
por: Liang, Zhuobin, et al.
Publicado: (2016)

Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes
por: Martin, Jacinta H., et al.
Publicado: (2018)

Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
por: Dong, Jun, et al.
Publicado: (2017)

Dual Roles for DNA Polymerase Theta in Alternative End-Joining Repair of Double-Strand Breaks in Drosophila
por: Chan, Sze Ham, et al.
Publicado: (2010)

Characterization of sequence contexts that favor alternative end joining at Cas9-induced double-strand breaks
por: Hanscom, Terrence, et al.
Publicado: (2022)

Either Non-Homologous Ends Joining or Homologous Recombination Is Required to Repair Double-Strand Breaks in the Genome of Macrophage-Internalized Mycobacterium tuberculosis
por: Brzostek, Anna, et al.
Publicado: (2014)

DNA Ligases I and III Cooperate in Alternative Non-Homologous End-Joining in Vertebrates
por: Paul, Katja, et al.
Publicado: (2013)

Nucleosome resection at a double-strand break during Non-Homologous Ends Joining in mammalian cells - implications from repressive chromatin organization and the role of ARTEMIS
por: Kanikarla-Marie, Preeti, et al.
Publicado: (2011)

γ-H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin
por: Kinner, Andrea, et al.
Publicado: (2008)

Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase
por: Karlsson, Karin H, et al.
Publicado: (2007)

Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11
por: Di Virgilio, Michela, et al.
Publicado: (2005)

Smarcal1 promotes double-strand-break repair by nonhomologous end-joining
por: Keka, Islam Shamima, et al.
Publicado: (2015)

In Silico Non-Homologous End Joining Following Ion Induced DNA Double Strand Breaks Predicts That Repair Fidelity Depends on Break Density
por: Henthorn, N. T., et al.
Publicado: (2018)

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination
por: Chitnis, Meenali M., et al.
Publicado: (2013)

Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining
por: Cullati, Sierra N., et al.
Publicado: (2023)

Necessities in the Processing of DNA Double Strand Breaks and Their Effects on Genomic Instability and Cancer
por: Iliakis, George, et al.
Publicado: (2019)

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells
por: Fattah, Farjana, et al.
Publicado: (2010)

CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
por: Quennet, Verena, et al.
Publicado: (2011)

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
por: Kefala Stavridi, Antonia, et al.
Publicado: (2020)

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
por: Head, PamelaSara E, et al.
Publicado: (2023)

To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection
por: Ackerson, Stephanie M., et al.
Publicado: (2021)

DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination
por: Biehs, Ronja, et al.
Publicado: (2017)

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF
por: Jessulat, Matthew, et al.
Publicado: (2021)

PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks
por: Couto, C. Anne-Marie, et al.
Publicado: (2011)

Subdiffusion Supports Joining Of Correct Ends During Repair Of DNA Double-Strand Breaks
por: Girst, S., et al.
Publicado: (2013)

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies
por: Mansour, Wael Y., et al.
Publicado: (2010)

Bridging of double-stranded breaks by the nonhomologous end-joining ligation complex is modulated by DNA end chemistry
por: Reid, Dylan A., et al.
Publicado: (2017)

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
por: Chakraborty, Anirban, et al.
Publicado: (2016)

Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system
por: Zhao, Bailin, et al.
Publicado: (2020)

The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining
por: Wang, Pei Lin, et al.
Publicado: (2022)

Correction to ‘DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining’
Publicado: (2023)

Competing roles of DNA end resection and non-homologous end joining functions in the repair of replication-born double-strand breaks by sister-chromatid recombination
por: Muñoz-Galván, Sandra, et al.
Publicado: (2013)

Essential Factors for Incompatible DNA End Joining at Chromosomal DNA Double Strand Breaks In Vivo
por: Ogiwara, Hideaki, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_8em411s5f4junsmda8valcnk7q