Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic

Abnormal presence of autophagic vacuoles is evident in brains of patients with Parkinson's disease (PD), in contrast to the rare detection of autophagosomes in a normal brain. However, the actual cause and pathological significance of these observations remain unknown. Here, we demonstrate a ro...

Descripción completa

Detalles Bibliográficos
Autores principales: Arduíno, Daniela M., Raquel Esteves, A., Cortes, Luísa, Silva, Diana F., Patel, Bindi, Grazina, Manuela, Swerdlow, Russell H., Oliveira, Catarina R., Cardoso, Sandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471400/
https://www.ncbi.nlm.nih.gov/pubmed/22843496
http://dx.doi.org/10.1093/hmg/dds309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471400/
https://www.ncbi.nlm.nih.gov/pubmed/22843496
http://dx.doi.org/10.1093/hmg/dds309

Ejemplares similares