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Benfotiamine Counteracts Smoking-Induced Vascular Dysfunction in Healthy Smokers

Background. Smoking induces endothelial dysfunction (ED) mainly by exacerbating oxidative stress (OS) and inflammation. Benfotiamine, a thiamine prodrug with high bioavailability, prevents nicotine-induced vascular dysfunction in rats. It remained unknown whether this effect also occurs in humans. M...

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Detalles Bibliográficos
Autores principales: Stirban, Alin, Nandrean, Simona, Kirana, Stanley, Götting, Christian, Veresiu, Ioan Andrei, Tschoepe, Diethelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471443/
https://www.ncbi.nlm.nih.gov/pubmed/23091724
http://dx.doi.org/10.1155/2012/968761