Encapsulation of cisplatin in long-circulating and pH-sensitive liposomes improves its antitumor effect and reduces acute toxicity

Cisplatin (CDDP) is one of the most effective and potent anticancer drugs used as first-line chemotherapy against several solid tumors. However, the severe side effects and its tendency to provoke chemoresistance often limit CDDP therapy. To avoid these inconveniences, the present study’s research g...

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Detalles Bibliográficos
Autores principales: Leite, Elaine A, Souza, Cristina M, Carvalho-Júnior, Álvaro D, Coelho, Luiz GV, Lana, Ângela MQ, Cassali, Geovanni D, Oliveira, Mônica C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471600/
https://www.ncbi.nlm.nih.gov/pubmed/23091378
http://dx.doi.org/10.2147/IJN.S34652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471600/
https://www.ncbi.nlm.nih.gov/pubmed/23091378
http://dx.doi.org/10.2147/IJN.S34652

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