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Inhibition of Cardiomyocytes Differentiation of Mouse Embryonic Stem Cells by CD38/cADPR/Ca(2+) Signaling Pathway

Cyclic adenosine diphosphoribose (cADPR) is an endogenous Ca(2+) mobilizing messenger that is formed by ADP-ribosyl cyclases from nicotinamide adenine dinucleotide (NAD). The main ADP-ribosyl cyclase in mammals is CD38, a multi-functional enzyme and a type II membrane protein. Here we explored the r...

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Detalles Bibliográficos
Autores principales: Wei, Wen-Jie, Sun, Hai-Ying, Ting, Kai Yiu, Zhang, Li-He, Lee, Hon-Cheung, Li, Gui-Rong, Yue, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471724/
https://www.ncbi.nlm.nih.gov/pubmed/22908234
http://dx.doi.org/10.1074/jbc.M112.392530